7 October


7:45

Registration

8:30

Welcome by Rudi Balling, Director, LCSB

8:40

Welcome by Rainer Klump, President, University of Luxembourg

8:50

Welcome by Rejko Krüger, President of GEoPD

9:00

Keynote by Michel Goedert, Head of the division of Neurobiology, MRC Laboratory of Molecular Biology, Cambridge
"The synucleinopathies: Twenty years on"

Session 1     

Mitochondrial Dysfunction & Dynamics (Moderator: Christine Klein)

10:00            

Clinical: Nobutaka Hattori, Chairman, Juntendo University School of Medicine
"Gene products of monogenic forms for Parkinson's disease and their links to mitochondrial and protein degradation pathways"

10:30  

Coffee break with guided poster session and industry exhibition

11:00

Translational: George Mellick, Chief Investigator, Griffith University
"Olfactory-derived cells as a model for Parkinson's disease"

11:30

Fundamental: Richard Youle, Senior Investigator, National Institutes of Health
"Damage Control and Parkinson's Disease: Roles of the kinase PINK1 and the ubiquitin ligase Parkin in the autophagy of mitochondria in vitro and in vivo"

12:00

Young researcher: Julia Fitzgerald
"The role of mitochondrial chaperone trap1 in Parkinson´s disease"

12:15

Frank Glod, Head of Unit Strategic Research Programmes, Luxembourg National Research Fund (FNR)
"Funding opportunities"

12:25

Lunch & guided poster session & industry exhibition

Guided poster tour (Moderator: Ronan Fleming, Manu Sharma, Alexis Elbaz)

12:30

Mini symposium by SynAging

Session 2

Connectivity & Excitability (Moderator: Thomas Gasser)

13:30           

Clinical: Jens Volkmann, Director and Chairman of the Department of Neurology, University Hospital of Würzburg
"DBS in PD: where do we stand and how may technical innovations help improving"

14:00

Translational: Caleb Webber, Program Leader, University of Oxford
"Profiling iPSC models of PD: Identifying therapeutics and single-cell approaches"

14:30

Fundamental: Peter Brown, Director, Medical Research Council Brain Network Dynamics Unit, University of Oxford
"Bad brain waves in Parkinson's and new approaches to putting them right"

15:00

Young researcher: Andreas Husch
"Supporting the Surgeon – Towards Intraoperative Data-Integration for Improved Deep Brain Stimulation Electrode Placement"

15:15

Coffee break with guided poster session

Session 3

Aggregation & degradation (Moderator: Jens Schwamborn)

15:45

Clinical: Jan O. Aasly, Consultant Neurologist/Professor of Neurology, St. Olavs Hospital
"Clinical phenotypes related to synuclein pathology in Parkinson´s disease"

16:15

Translational: Markus Britschgi, Principal Scientist in Neuroscience Discovery, Roche
"PRX002, a Mab targeting alpha-synuclein for disease modification in Parkinson's disease: from preclinical models to first in humans"

16:45

Fundamental: Maria Grazia Spillantini, Professor of Molecular Neurology, University of Cambridge
"Alpha-synuclein synaptic dysfunction in Parkinson’s disease"

17:15

Young researcher: Pierre Garcia
"Neurodegeneration is independent of α - synuclein aggregation in a mouse model of "prion like" - synuclein spreading."

17:30

Wrap-up by Rejko Krüger, President of GEoPD

18:30

Social event "A night at the furnace", Reception, dinner & cultural heritage